Welcome to The Johnjay Van Es Podcast!
Oct. 15, 2026

Why Earlier Information Changes Everything: A Conversation With Dr. Simon of SimonMed

How a Radiologist Ends Up Building a Nationwide Imaging Company

What drives someone to take a medical specialty that typically operates behind the scenes and turn it into a patient-facing healthcare business?

An obsession with access, technology, and prevention. Dr. Simon describes a straightforward but consequential insight: earlier information changes outcomes. When the goal shifts from reacting to symptoms toward actively monitoring health over time, the entire value of imaging changes. SimonMed is built on that premise, making advanced diagnostic imaging available at a reasonable price in a patient-friendly setting rather than limiting it to major hospital systems.


What Interventional Radiology Actually Involves

How does a background in interventional radiology shape how Dr. Simon evaluates new technology?

It grounds everything in precision. Interventional radiology means the radiologist is not only reading scans but performing minimally invasive procedures: embolization to stop bleeding, angioplasty to open vessels, catheter-based treatments that produce immediate results. That hands-on experience with targeting and technique carries directly into how he thinks about imaging hardware, AI tools, and outpatient capabilities. Faster scanners, better MRI and CT hardware, and computing advances have made it possible for outpatient imaging centers to perform exams that used to require major hospital infrastructure, including cardiac imaging that can freeze heart motion.


What Longevity Clinics Around the World Are Actually Doing

What did Dr. Simon find traveling as his own secret shopper to longevity clinics in London, Shanghai, and the Netherlands?

A combination of diagnostics working together: MRI, ultrasound, hearing tests, lab work, and rapid specialty consults aimed at catching disease early rather than confirming it late. The workflow and patient experience are as important as the technology. His upcoming Simon 360 concept pairs whole body imaging with muscle strength and power measurement, addressing sarcopenia, which starts earlier than most people expect, and the decline of type II muscle fibers that can be accelerated by rapid weight loss and GLP-1 medications. Making aging well measurable rather than vague is the goal.


Brain Health Beyond Memory

What does Dr. Simon mean when he emphasizes cognition and processing speed rather than just memory?

That memory is a late-stage indicator. Processing speed and white matter connections in the brain offer earlier signals. Research directions he describes include TMS and low intensity focused ultrasound to influence brain activity with greater precision. On the imaging side, he emphasizes refusing to dismiss findings as incidental and treating the brain with the same longitudinal monitoring approach applied to the heart and body.


Heart Disease Prevention and What Standard Screening Misses

Why is a zero calcium score not the reassurance most people assume it is?

Because soft plaque, which is dangerous and unstable, does not calcify and therefore does not show on a calcium score test. CT angiography combined with AI analysis can track plaque changes over time and catch what calcium scoring misses. Cardiac strain offers a deeper view of heart function than ejection fraction alone. Liver fat measurement adds metabolic risk context. The consistent message across every system is the same: prevention requires seeing what is happening early, tracking it objectively, and acting before what gets called normal aging becomes avoidable decline.

Related Episode

Oct. 9, 2026

"Most of What Kills Us Is Preventable": A Longevity Doctor's Wake-Up Call

Could a full-body MRI reveal health risks you don't even know you have? Dr. John Simon, founder of SimonMed Imaging, shares how advanced medical imaging is changing the way we approach cancer screening, early detection, and preventive healthcare. With more than 30 years of experience in radiology, Dr. Simon has helped expand access to advanced diagnostic imaging, including MRI and CT scans. He explains what full-body MRI can reveal, how cardiac imaging can uncover potential heart risks...